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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d45e76c60cc7d634a3783b781caec1415b138860cedd34d59c677d3f5dd91c7' 
  AND token = 'TgTgmsDJCndegA7JwbV1FG00SgZv13NtIrRk/7h7Gs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}