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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ceeaf6df30a0aab1bf72a5f4c4786a14424b45ada71e2916ea6641580fb330d' 
  AND token = '8o2aTm/lKhRAY6l8fBFzA9g9XECMRgAaGF72ZvXp8Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}