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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a8b50e6d39d0730e50d588b2d36de1f9ed7e5db38d1a70907dc06f3539177f' 
  AND token = '6hZGlsmBugUdgD+WikNxCqKsE6oK7Wo12a2UiG1PMUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}