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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3d1e9850d197f55e99dfe49d54fcd68c0c0daa1179f775db12464c8e515946' 
  AND token = 'VcsMWVu9OyZRWC5Zc8l7SSe+dtzoESlAU+h3dytH7Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}