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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef15741394a3f45f23b8e3cfba4f3a6174a0727eb47191222dbb9d7db52484a6' 
  AND token = '0u75rYyNYs3hxUz5u+Z3O1OFno2vUqfTQnpGEf5ebzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}