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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572cf7cf12496e9c1f3e16118f87019e5dc81872508a4d4e9893d9041c29128b' 
  AND token = 'vB72YLYCqXiCIz0uaHwX2FadKtUBu583bN2j236/fwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}