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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f8de8ead3a8d5c2c836d01da37258dd2815adaa4025f9e88cbc13483a64185' 
  AND token = 'F74oesQKvnFb06crzePpN6H8yL808khhwHb4gk7UaMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}