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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643f5b23cd497437cc63e2d514991b2ded0612dfc6730ad32a5f4f42bdf76fea' 
  AND token = 'ojs5CA+u2anFzGKGUn6nTPX47/KABUJX63Oa5TsDzfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}