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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aba3a4cc6f74e95d2e0a86fb04df6207f09da7328e566030c01f27e4fc6ee01' 
  AND token = '1VXsuv4rI1lY5bRjUNc5dDKRXaiK6IJw9FMfeFWS0sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}