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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8366e18d306799f99085ca229cd22cfa40e2b8e0159c2fe47c7c73e9e48d32e' 
  AND token = '0jsGeFnS72Hxy7Rdk7YGBd6XOC/xj/x4xN1LroMh9fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}