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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a5348dc20bf6ef753b22c2c0d027ba6ca0ef2ec2ce7e4a6225f1b3319a7013' 
  AND token = 'WHX2CotE7yaZc+CGZFPMxXTHVkfo3X0QjfLcCX3e/xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}