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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d6d0d0c900029c80477857e31ee0f179d8f5513c006dc369bc0fe617bf36fc' 
  AND token = 'c/HzKIi/uFMdO9Cee7lTBGo3ZBzVlAlMDCquIhwLr9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}