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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1243c4048c0069340809b3eb10a7889e0ad2d321e5451f2ce9674ea0c75495be' 
  AND token = 'KzpFKBW4ixrnPmJlfsry3/gE0l3B2HRnpS6c6IrAOc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}