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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1190a1ba6670ac05a1ab59aa7fa1aa1ca21c787a5e9f8a180e409cbca82e2465' 
  AND token = 'e42/bVmStQh1XG69uxUc13W26IRKfixPX5lbKsHp2N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}