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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87acd1bb369e7a98bb164f362ff01a012d9fcd2292c12c1654bf83d0a87f7197' 
  AND token = 'pFhUbBUGVNvqpHpRDwLqB9p2DNQ/GI3OrOpcafSIUt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}