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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4e81f7c68e110ad8754bbf9f692e9bd8350201b1edaf54e6a887c8d26e1f5f' 
  AND token = 'HPQFMyq6JhOaYSUeMR/bjI9vle7QTVkI7PitbvDifn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}