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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '638a15651ca8e82a27884bcbc3e932554613af8608899278f455e1ba12ca359e' 
  AND token = 'Qr0qFjZJDD/xsqpv23r+TGn+LmaKO0W4dmb9Ndo+44k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}