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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c7920b6bc4cb85d40b4d46d2839fee4dcc80f2d2c672e3862cfc59bbbca74a' 
  AND token = '/XWVUzQVbeWkwfhczYQFlfm1Cy7iycIRvPTR9Rk8VC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}