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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7725ee7f98a3ac11905bff49163946d64634e3fec6e1e8106ac9bf0d601f9cc' 
  AND token = 'Jqezj94ateU+AhkKzYSDC4MDE8zyb6Jyp7bdAcXzNlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}