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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fcfc13cd8ff6fc192e5d912f95c048a1c2f90b95dbc071caa06b36bf485a967' 
  AND token = 'XkaEj3QVW6rBXx+20BKqOZzomv8vfpa3LZ55FJydSFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}