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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25f344a18102e7f4fd5fd53936f62dc5a63bbc04f786ded079b3801d34c8de2' 
  AND token = 'V9PwPcwoSgF3cPxCuIewtJSawaM9ORuQNnppr+CRq3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}