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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4c7def1589187d33cbd4fb796cab6a22dedd04c1df28e6c52244936bdcfd52' 
  AND token = 'sno1Z+/qDwzs3EYwXw8EoWwARUbFdF+JN334hlNYayM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}