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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f21604c4debc811b81dea6b724f9e18dc08e9652d7264d1a669409a9c881a5f' 
  AND token = 'l0/mAI7SF1ZHDbUY2bbVlJP8dnGh5Xajvmlmupuj/Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}