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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49e5e85717051ccb706b92951116f3bd2e826a9780c26f45cea99b333dcc346' 
  AND token = 'RR8NnY1pHsnMSVwueapk0YDe+86Y6r5vcERdCqDYNu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}