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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e5be520f43d0789020481015362e58722c6eaa15fb80af847893aee32d52ad' 
  AND token = 'Z4HT6mDhYgDx1/aVJiI/r2+l6MLol5Walz6xtIHLfvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}