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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322a8eff77d32a15ab9eaa422a4ff428ba237e6c7234a44aad079a92fe88756b' 
  AND token = 'VP04Bh67fHpvfsb6DkW/X5EWpyexrJGCvGYgAA+/JkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}