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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9c582022f971a6b70eb261e90c7abbf12d4c025cf30665aecfb43a69b458a0' 
  AND token = 'UXkuupjxT0Boz95m2i6s5C1bp0d3L4doXixJq42zTMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}