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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c9c5c64950e9a6d6e13f42c32914e2d80f418922e360b859dad52d466f1760' 
  AND token = 'vLYTe/ZFzib8I5+LcFw6H4EQ52VTchdbhRF49BRMZ+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}