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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1898281720f4d31ee5bad71d582a3de43caf533a014259eee06261ff4baa2b27' 
  AND token = 'zZ3fxlzS4lXbyfDo8iJZgo+k/OWb6adK8zwBSJUJPxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}