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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17be3caf412fa1d01c6f2fb1b421b005b97d8894d2fe7e39029193115038e953' 
  AND token = 'f6r4SQUFiBILRDWdFwV0IYgDwm0DhoOBb1WcsldAXB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}