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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a65ed12bb9481b6732ded93703d36c733ec6dd29065e2f00d29b022a09ccc30' 
  AND token = '9bipCShO6XlMRGMEx0GKhMACnA0m6AXeoGDfgzy4Asw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}