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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9da8054f51cdf8ef40bfcce8ca1109172ba851c8f77712b2c36a169c0d0be58a' 
  AND token = 'qHz0DstqW4Kikk09MXmK5a8DcFuNzL+hFj+KENkrIz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}