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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bbed818c97e6fe28b36ff2b3d705feda70478c92ef1ebbab0c22a61d2ec1f0' 
  AND token = 'Tubt071rVi91ZbTXJwbYuNuEkuYscOG2UBpVJkUyVl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}