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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6380d99ea7c16d3786484bc5ef6bc718a6b0a46f109c02ded2eef7a98308cc8f' 
  AND token = 'a4EN9MdylAlK/VuXAWyXB02d0ERZjb9S05vbPVjDdjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}