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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6436a3edf9fc7277122e2b0fac1e8ece5eb2fcb0d9f0386d51932bb70d3a3fdb' 
  AND token = 'QE7RH14K6S5EhxmxmWXLt903l4E4w8CiuS3Fl5343pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}