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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '623d01c0fb06430fa40442ea354ab6b31fbccf3679f24a946f4673512f4aaa68' 
  AND token = 'ZbrC1i7mN0icYiBBKbTFpCb6VuCTgpc3P2i+I1G09Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}