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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48e8ef8496e75c197a0a45e425103cd4a48bf1eca7b98f397759b7e0e0828ad' 
  AND token = 'Lox1xL1G/jSON9kMEyDKHeyGvN9UWQh7wKpnskF2Kfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}