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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4617c1127cae1104ea0a8211ddef7c642e118839e4f204befcf773cd279e94' 
  AND token = '1a4wMdoiJ5ONEBtGnL/UsiGmIDCCXPr/1f4h96/8NnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}