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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3f83b0bddda72ce16dc41174120e3280fae988b7dc6eb3dfc2133961f52da36' 
  AND token = 'Beem521ZgTjOEhw8mvK0fAbomAjbhmLdwWC8BPzFgtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}