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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a6c9aaa9b537bf564d4aade996bd845fcf3610ef474d7852f725d22d04c930' 
  AND token = '0Pk78FJkEEl5oYOC8azGFKUETM5lV1XUW4TVSsee0Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}