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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe36a485c418babb3bb804fa60d8a2262880950c947f0c57598d0c0c246c559' 
  AND token = 'U5tIlLFuUmpulLpJDco6io1G9HD/bxJAck95oI7C04o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}