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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c9726e10a9d2481eac542f4d3965decbdacb8bf48a251b60bc19df51b680f82' 
  AND token = 'EGFWxutWDLyeFApPsAjUzC2VWCrM9rFeLNI+HS4l9TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}