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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c629f757e9b8f7d8ee874961b0fbc7b7a3c224a8f2a5271a9303bca6847846' 
  AND token = 'azPZ4f88kse+5GHT1nVCGKq3sBvSiDqibDbueNn2Bfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}