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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af891f56702e0b72963af8446023ad491cd7a3ecc5b2ea6da1d34c4edec4cdb5' 
  AND token = 'Mdu/y424DQGm9OkjgOcoNonKk6Z3OGxExsAlabH7b2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}