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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1351f2aa38c00c5d44c85a78157321ba54f8fd4b4ea16a27cb612d3fc5ad2e75' 
  AND token = 'XvoK9zvu89GJfX3FK5XDt3w8zwSIkXUDJ38KOqMRzo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}