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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353325bff9cd044e175202de0e5c90807d44c993f39c5ec3683340268b85da63' 
  AND token = '7GflqDC25PjAUcBhFCmkwe4AC9dzAhB3ekx5IL7GWEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}