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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '974811e341457e6041aeae74cee6e5d032a9aa76a9e8f303bc048615eeffd480' 
  AND token = 'NG+KFxqki3zls0O/H0HZa4nEMT9bQZuU3SL8GM5GJ8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}