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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '532260198977a835d0c4b3c767999ff7cc9c56db44486ba2df0dc87d93870e4d' 
  AND token = 'G4r/m5yinFI8amm0eS9u5EGiOtuYqhBzlpsZOsJRRI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}