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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab0f6161fb6fd235d81f357e2f900cb8e37ec64b6a87a96df26a24cb91794151' 
  AND token = '5wo047PuphlUaXN14PEZR9r0DYq+w3azZqY46niDYdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}