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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '636e5b5e96a5fe7f4848931348fca0f2f77127dbf6018de64c8bd3c476a2612d' 
  AND token = '/vnx7kpAbWBhEJsFa7xapQ5G6AtE+5yz8jNRTrsA4ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}